Decoupling of reaction time-related default mode network activity with cognitive demand

Default Mode Network: Granger causality characterization of cognitive state changes

Introduction Characterization of the default mode network (DMN) as a complex network of functionally interacting dynamic systems has received great interest for the study of its neural mechanisms [1-4]. However, it is still unclear how DMN sub-regions interact during resting state and how these interactions change when performing a task. Granger causality can be used to explore causal relations...

Brain's Default Mode Network

[The default mode network: cognitive role and pathological disturbances].

INTRODUCTION A "resting state" or "default mode network" has been highlighted in functional neuroimaging studies as a set of brain regions showing synchronized activity at rest or in task-independent cognitive state. STATE OF THE ART A considerable and increasing number of studies have been conducted over the last few years so as to unravel the cognitive function(s) of this brain network. P...

APOE Effects on Default Mode Network in Chinese Cognitive Normal Elderly: Relationship with Clinical Cognitive Performance

BACKGROUND Functional connectivity in default mode network (DMN) may be changed in Alzheimer's disease (AD) patients and related risk populations, such as amnestic mild cognitive impairment (aMCI) patients and APOE ε4 carriers. Exploring DMN changes and related behavioral performance of APOE ε4 population might provide valuable evidence for better understanding the development of AD. METHODS ...

Default Mode Network (DMN) Activity during Olfactory Processing

Introduction: The dynamics of resting state networks during active and passive task performance has received increased attention in recent times [1, 2]. Several studies have reported modulations in the default mode network (DMN) (or deactivations) during the performance of sensoryand cognitivefMRI tasks [1, 2, 3]. However, no study has investigated such modulations in relation to olfaction. Usi...